The Computational Biophysics Group (CBG) at UCI develops theoretical and computational methods to study complex biological systems. We focus on developing a molecular understanding of the essential machinery of life. Our research lies at the intersection of physics, biology, and chemistry, and is often carried out in close collaboration with leading experimentalists.

Recent Publications

Phosphorylation at Ser65 modulates ubiquitin conformational dynamics
Structure 31 (7) 884-890.e2 (2023)
Phosphorylation at Ser65 modulates ubiquitin conformational dynamics
Strain and rupture of HIV-1 capsids during uncoating
Proceedings of the National Academy of Sciences, 119 (10), e2117781119, (2022)
Strain and rupture of HIV-1 capsids during uncoating
Cooperative multivalent receptor binding promotes exposure of the SARS-CoV-2 fusion machinery core
Nature Communications 13 (1), 1-12, (2022)
Cooperative multivalent receptor binding promotes exposure of the SARS-CoV-2 fusion machinery core