Gregory A Voth

Latest

• Strain and rupture of HIV-1 capsids during uncoating
• Cooperative multivalent receptor binding promotes exposure of the SARS-CoV-2 fusion machinery core
• Integrin-based mechanosensing through conformational deformation
• A multiscale coarse-grained model of the SARS-CoV-2 virion
• Temperature and phase transferable bottom-up coarse-grained models
• Atomic-scale characterization of mature HIV-1 capsid stabilization by inositol hexakisphosphate (IP6)
• TRIM5α self-assembly and compartmentalization of the HIV-1 viral capsid
• Off-pathway assembly: a broad-spectrum mechanism of action for drugs that undermine controlled HIV-1 viral capsid formation