The Computational Biophysics Group (CBG) at UCI develops theoretical and computational methods to study complex biological systems. We focus on developing a molecular understanding of the essential machinery of life. Our research lies at the intersection of physics, biology, and chemistry, and is often carried out in close collaboration with leading experimentalists.

Recent Publications

A conifer metabolite corrects episodic ataxia type 1 by voltage sensor3 mediated ligand activation of Kv1.1
In Review
A conifer metabolite corrects episodic ataxia type 1 by voltage sensor3 mediated ligand activation of Kv1.1
Phosphorylation at Ser65 modulates ubiquitin conformational dynamics
Structure 31 (7) 884-890.e2 (2023)
Phosphorylation at Ser65 modulates ubiquitin conformational dynamics
Strain and rupture of HIV-1 capsids during uncoating
Proceedings of the National Academy of Sciences, 119 (10), e2117781119, (2022)
Strain and rupture of HIV-1 capsids during uncoating